Autoimmune: The Cause and the Cure - Annesse Brockley, Kristin Urdiales - Google книгиOne such theory speculates that due to the rapidly accumulating pollution in the environment we are now exposed to more chemicals than ever before and this could be the reason why autoimmune diseases are plaguing us at a higher rate than half a century ago. Another theory puts a different spin on recent developments. According to the hygiene hypothesis, we live in a much safer world than our great-grandparents did — we have antibiotics now, vaccines, sterile environments and we raise children with much more caution. The proponents of this theory reason that this newfound safety from infections and germs leaves our immune system with almost nothing to fight and thus, no way of knowing friend from foe. Heredity, however, cannot be ruled out as a risk factor. With many variables and unknowns, there a few things we do know about autoimmune disease.
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The cause of liver cell destruction in this disease is unclear, but may be related to an imbalance in some of the immune system cells effector and regulatory. The persistent inflammation within the liver observed in AIH can result in scarring, ultimately leading to cirrhosis, liver failure requiring a liver transplant, and even death. AIH is about 4 times more common in females than males and is commonly associated with other autoimmune conditions including type 1 diabetes, Hashimoto's thyroiditis, and celiac disease. There are two clinically relevant types of AIH, including type 1and type 2. Type 1 AIH, also referred to as the classic type, is typically diagnosed in adulthood, whereas type 2 is diagnosed during childhood. Both types are treated similarly; however, type 2 AIH can be more severe and more difficult to control. Symptoms associated with AIH include fatigue, itching pruritus , yellowing of the skin and whites of the eyes jaundice , nausea, vomiting, abdominal pain, weight loss, light colored stools, dark colored urine, joint pain, rashes, and loss of menstruation in women.
Autoimmune diseases have common properties characterized by abnormal blood chemistry with high serum autoimmune antibodies, and inflammatory mediators.
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When we get sick we naturally want to understand what is happening to us. Our first question is: What is it? We want to put a name to our suffering by establishing a diagnosis. For many illnesses, there are no good answers to those questions. We want a definitive answer; we want to understand what caused the illness.
As a result, many patients turn to lifestyle and diet changes—i. According to Dr. Steven Gundry , a celebrated heart surgeon and cardiologist who transformed his entire career to treat these difficult cases, autoimmune diseases have their root in our gut microbiomes. Since starting his Palm Springs clinic, Dr. Gundry has reversed thousands of autoimmune cases, using diet as an environmental variable to manipulate our genes and the genes of our microbiome.
A new study has raised the possibility that stress may cause autoimmune disease, such as lupus or rheumatoid arthritis, because it found a higher incidence of autoimmune diseases among people who were previously diagnosed with stress-related disorders. There are scores of autoimmune diseases out there. Some of the most well-known are rheumatoid arthritis , psoriasis, multiple sclerosis, and type 1 diabetes. But an infection could do the same thing. This serves us well if chased by a lion.